| I |
PROHIBITED CLASSES OF SUBSTANCES |
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a. Stimulants
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b. Narcotics |
c. Anabolic Agents |
| d. Peptide hormones, mimetic and analogues |
e. Diuretics |
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| II |
PROHIBITED METHODS |
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a. Blood doping
b. Pharmacological, Chemical and physical manipulation |
| III |
CLASSES OF DRUGS SUBJECT OT CERTAIN RESTRICTIONS |
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| a. Alcohol |
b. Cannabinoids |
c. Local anaesthetics |
| d. Corticosteroids |
e. Beta-blockers |
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| I |
PROHIBITED CLASSES OF SUBSTANCES |
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Prohibited Substances fall into the following classes of substances |
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a. Stimulants
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b. Narcotics |
c. Anabolic Agents |
| d. Peptide hormones, mimetic and analogues |
e. Diuretics |
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All Substances belonging to the prohibited classes cannot be use even if they are not listed as examples. For this reason, the term "and related substances" is introduced. This term describes drugs that are related to the class by their pharmacological action and /or chemical structure. |
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| A. |
Stimulants |
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Prohibited substances in a class (A) include the following examples : |
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amineptine, amiphenazole, amphetamines, bromantan, caffeine*, carphedon, cocaine, ephedrines**, fencamfamin, mesocarb, pentatrazol, pipradrol, salburamol***, Salmeterol***, terbutaline***, and related substances. |
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* For caffeine the dedinition of a positive is a concentration in urine greater than micrograms per milliliter. |
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** For ephedrine, Cathine and methylephedrine, the definition of a positive is a concernation in urine greater than 5 micrograms per milliliter. For phenylpropanolamine and psedudoephedrine, the definition of a positive is a concerntration in urine greater than 10 micrograms per milliliter. If more than one of these substances are present below their respective thresholds, the concentration should be added. If the sum is greater than 10 micrograms per milliliter, the sample shall be considered positive. |
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*** Permitted by inhaler only to prevent and/or treat asthma and exercise induced asthma. Written notification of asthma and/or exercise-induced asthma by a respiratory or team physician is necessary to the relevant medical aurhority. |
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Note : All imidazole perperations are acceptable for topical use, eg. oxymetazoline. Vasoconstrictors. (e.g. adrenaline) may be administered withlocal anaesthetic agents. Topical Preparations (e.g. nasal, ophthalmological) of phenylephrine are permitted. |
| B. |
Narcotics |
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Prohibited substances in class (B) include the following examples: |
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buprenorphine, dextromoramide, diamorphine (heroin), methadone, morphine, pentazocine, pethidine, and related substances. |
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Note : codein, dextromethorphan, dextropropoxyphene, dihydrocodeine, diphenosylate, ethylmorphine, pholocodine, propoxyphene and tramadol are permitted. |
| C. |
Anabolic agents |
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Prohibited substances in class (C) include the following examples : |
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1. Anabolic androgenic steroids |
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| a. |
clostebol, fluoxymesterone, metandienone, metenolone, nandrolone, 19-norandrostenediol, 19-norandrostenedione, oxandrolone, stanozolol and related substances |
| b. |
androstenediol, androstenedione, dehydroepiandrosterone (DHEA), dihydrostestosterone, testosterone*, and relates substance |
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Evidence obtained form metabolic profiles and/or isotopic ration measurements may be used to draw definitive conclusions. |
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* The presence of a testosterone (T) to epiestostrone (E) ration greater than six (6) to one(1) in the urine of a competitor constitutes on offence unless there is evidence and this ratio is due to a physiological or pathological conditions, eg. low epitstosterone excretion, androgen producing tumor, enzyme deficiencies. |
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In the case of T/E greater than 6, it is mandatory that the relevant medical authority conducts an investigation before the sample is declared positive. A full report will be written and will include a review of previous tests, subsequent tests and any results of endocrine investigations. in the event that pervious tests are not available, the athlete should be tested unannounced at least once per month for three months. The result of these investigations should be included in the report. Failure to co-operate in the investigations will result in declaring the sample positive. |
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2. Beta -2 agonist |
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When administered orally or by injection. |
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bambuterol, clenbuterol, fenoterol, formoterol, reproterol, salbutamol* terbutaline* and related substances. |
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* authorized by inhalation as described in article (I.A) |
| D. |
Diuretics |
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Prohibited substances in class (D) include the following examples |
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acetazolamide, bumetanide, chlorthalidone, etacrynic acid, furosemide, hydrochlorothiazide, mannitol*, mersalyl, spironolactone, triameterene, and related substances. |
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* Prohibited by intravenous injection. |
| E. |
Peptide hormones, mimetic and analogues |
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Prohibited substances in class (E) include the following exampless and their analogues and mimetics : |
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1
Chorionic Gonadotrophine (hCG)
2 Pituitary and synthetic gonadotrophins (LH)
3 Corticotrophins (ACTH, tetracosactide)
4 Growth hormone (hGH)
5 Insulin -like Growth Factor (IGF-1)
and all the respective releasing factors and their analogues
6 Erythropoietin (EPO)
7 Insulin |
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Permitted only to treat insuline -epepndent diabeties. Written notification of insulin-dependent diabetes by an endocrinologist or team physician is necessary. The presence of an abnormal concerntration of an endogenous hormone or its diagnostic market(s) in the urine of a competitor constitues an offence unless it has been consclusively documented to be solely due to a physiological or pathological condition. |
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| II |
PROHIBITED METHODS |
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The following procedures are prohibited : |
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Blood doping is the administration of blood, red blood cells, artificaloxygen carriers and related blood products to an athlete. |
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Pharmacological, Chemical and physical manipulation |
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Pharmacological, Chemical and physical manipulation is the use of substances and of methods which alter, attempt to alter, or may reasonably be expected to alter the integrity and validity of samples used in doping controls. These include, without limitation, the administration of diuretics, catheterisation, samples substitutions and or tampering, inhibition of renal excretion such as by probenecid and related compounds, and alternations of testosterone and epitestosterone measuremtns such as epitestosterone* or bromantan administration. |
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*An epitestosterone concentration in the urine greater than 200 nanograms per milliliter will be investigated by studies as in Article (I C. I b) for testosterone. |
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The success or failure of the use of a prohibited substance or method is not material. It is sufficient that the said substance or procedure was used orattempted for the infraction to be considered as consummated.
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| III |
CLASSES OF DRUGS SUBJECT OT CERTAIN RESTRICTIONS |
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| A |
Alcohol |
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Where the rules of a responsible authority so provide, tests will be conducted for ethanol. |
| B |
Where the rules of a responsible authority so provide, tests will be conducted for cannabinoids (e.g. Marijuana, Hashish). A concertration in urine of 11-nor delta 9-tetrahydrocannabinol-9-carboxylic acid (Carboxy-THC) grater than 15 nanograms per milliliter is prohibited. |
| C |
Local anaesthetics |
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| a |
bupivacaine, lidocaine, mepivacaline, procaline etc. can be used but not cocaine. Vasoconstrictor against ( eg. adrenaline) may be used inconjunctioin with local anaesthetics. |
| b |
Only local or intra articular injections may be administrated |
| c |
Only when medically justified. |
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Where the rules of a responsible authority so provide, notification of administration may be necessary.
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| D |
Corticosteroids: |
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The systemic use of corticosteroids is prohibited. Anal, aural, dermatological, inhalational, nasal and ophthalmological (but not tectal) administration is permitted. Intra-articular and local injections of norticosteroids are permitted. Where the rules of a presponsible authority so provide, notification of administration may be necessary.
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| E |
Beta -blockers |
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some examples of beta-blockers are: |
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acebutolol,alprenolol, atenolol, labetalol, metoprolol, nadolol, oxprenolol, propranolol, sotalol and related substances
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Where the rules of an international sports Federation so provide tests will be conducted for beta- blockers.
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